The History of EECP

The device used for EECP was invented in the late 1950s at Harvard University.


In 1950s

Harken and Associates and Birtwell developed counterpulsation techniques at Harvard University. Continue Reading

In Mid 1960s

Several scientists evolved counterpulsation to a noninvasive technique using a primitive external device that applied pressure generated by a hydraulic system.Studies with early non-invasive machines demonstrated the potential to increase survival in patients with myocardial infarction, cardiogenic shock and angina pectoris. Pneumatic devices soon replaced the cumbersome hydraulic machines. Continue Reading

In the late 1960s

External Counterpulsation (ECP) was developed in the 1960s as a circulatory assist device to support patients in acute myocardial infarction and cardiogenic shock. In the next five years, Dr. Z.S. Zheng in China developed a pneumatic sequential counterpulsation system ushering the modern era of Enhanced ECP. Continue Reading

During the 1970s

Zheng and colleagues at Sun Yat Sen University in China reported studies with a newly designed sequenced pulsation system using four sets of compression bladders on the patient’s legs, buttocks and arms. In these trials, effects of the sequenced system were studied in patients with angina pectoris and acute myocardial infarction. In more than 90… Continue Reading

In 1970s

The FDA approved EECP for treatment of cardiogenic shock and my ocardial infarction (heart attack). Continue Reading

In 1970s

EECP was in use for acute myocardial infarction and cardiogenic shock. The U.S. Food and Drug Administration cleared EECP in: Continue Reading

In 1980

China began developing extensive technological advancements with EECP and continues to make positive strides. Continue Reading

In 1989

researchers from the State University of New York at Stony Brook determined that enhanced external counterpulsation continued to show helpful effects on patients even three years after treatment. Continue Reading

In 1995

EECP was approved by the FDA for chronic stable angina pectoris. Continue Reading

After 1995

The Health Care Financing Administration (HCFA) denied , manufacturer of EECP technology, application to approve EECP for angina. The given reason was that HCFA required a double-blind clinical study and publication of research in peer-review journals. Continue Reading


Sara Soulati began treating patients with EECP working at EECP West Inc, the only clinic in the U.S. outside of Stony Brook in New York. EECP West introduced EECP treatment to Dr. Julian Whitaker. Sara treated many patients with all types of illness referred by Dr. Whitaker’s practice. Continue Reading


Sara Soulati worked with various manufacturing companies like Nicore and Cardiomedics. Sara Soulati teamed with HealthSouth sports rehabilitation facility in Los Angeles to study the effect of EECP on athletes’ recovery from injury. Continue Reading


Sara Soulati became the leading sales person for Vasomedical and tried to open the EECP marketplace so people could receive treatment by selling the technology and educating physicians. Continue Reading

On December 16, 1998

Vasomedical presented to HCFA results of its Multicenter Study of EECP (MUST Trial) featuring seven medical centers and 139 patients in a double-blind study relating to Class I, II and III angina. HCFA’s Grant Bagley, MD, director of HCFA Coverage and Analysis, again denied coverage stating results of the MUST Trial needed to be published… Continue Reading


Sara Soulati became business partner at Cardiac Renewal Centers of America, a privately held management company for 10 EECP centers in Southern California. Continue Reading

July 1999

The Center for Medicare Services guidelines for EECP approved. Enhanced External Counterpulsation (EECP) is a non-invasive treatment developed for treatment of end-stage angina pectoris that is refractory to conventional therapy, (i.e. surgery, angioplasty), acute myocardial infarction, cardiogenic shock. A person’s coronary anatomy is not readily amenable to such procedures. Continue Reading

In 1999

After CMS failed to approve EECP for angina again, Wallace Haselton, a former member of Vasomedical’s board of directors, went head-to-head with HCFA to secure coverage of EECP for angina. He called Senator Edward Kennedy (D-Mass.), and together they petitioned the Senate Finance Committee, regulators, legislators and anyone they could enlist to help change the… Continue Reading

February 2000

HCFA changed all references of EECP to ECP in written materials. These coverage guidelines issued by HCFA went unchallenged by the medical industry or manufacturers of EECP technology. These limited coverage guidelines remain in force today. Continue Reading


Sara Soulati works with Los Angeles Avengers Arena Football team to further her study of EECP and elite athletes. Sara Soulati writes clinical research paper with UCLA cardiologist on EECP and sports. Winning Edge Technologies, Inc. is a Sara Soulati company. Continue Reading


Sara Soulati launches Global Cardio Care® Inc. working with physician practices that deliver EECP care so people suffering from cardiovascular disease could finally get the treatment they needed. Continue Reading

In 2002

The American Heart Association and the American College of Cardiology issued guidelines on treating angina stating that more studies are required on EECP before it can be recommended as a standard treatment for angina. So far, EECP has not been widely accepted in clinical practice. Continue Reading

In June 2002

the FDA approved EECP for treatment of congestive heart failure. Continue Reading

In 2004

several studies also found that EECP shows some benefit for patients with stabilized heart failure. Continue Reading

January 2005

CMS denied the request by Vasomedical to approve Medicaid reimbursement of EECP for congestive heart failure, advanced stages of angina, ardiogenic shock or coronary artery disease. Continue Reading

Since 2005

clinical researchers have continued to publish studies on the efficacy of EECP in support of disease treatment. Continue Reading

December 20, 2005

Vasomedical released results of its Prospective Evaluation of Enhanced External Counterpulsation in Congestive Heart Failure (PEECH) study for congestive heart failure and published results in a peer-review journal. This study found that patients with mid- to moderate-severe heart failure experienced an improvement in their New York Heart Association (NYHA) class after counterpulsation. However, the long-term… Continue Reading

Significant Landmark Study January 1, 2010

“EECP is a Regenerative Therapy,” published in Frontiers in Bioscience magazine, clinical researchers from Texas A&M Health Science Center College of Medicine and Cardiology showed that EECP therapy is likely to regenerate circulatory stem cells of diseased organs in the body. Continue Reading


Sara Soulati opened a new EECP center, Global Cardio Care—West Los Angeles. Continue Reading

At Global Cardio Care centers, the history of EECP is shared with people who have a variety of diseases (not only end-stage cardiovascular disease). Cardiovascular diseases can be treated with EECP therapy. We focus on prevention of cardiovascular disease and education, not just end-stage of life treatment. That’s how we differentiate Global Cardio Care services over other institutions. There are more than 900 academic institutions and independent physician practices throughout the U.S and the world that use EECP therapy for cardiovascular disease. They include:

  • University of California Los Angeles
  • University of California San Diego
  • Duke University Medical Center
  • University of Pittsburgh Medical Center